Liver cells can be divided into the membrane portion and a cytosolic portion. Which of the following molecules would be associated with the cytosolic fraction?
A. Phospholipase C-beta
B. Activated G-alpha subunit
C. Inositol 1,4,5 tris-phosphate (IP3)
D. Activated PKC
E. PI 4,5 bis-phosphate (PI(4,5)P2)