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24yo F presents w:uncontrollable nose bleed for 6hrs which is her 4th nose bleed over past 2w + heavier than usual menses over last 2 cycles + no hx of bleeding problems w previous surgery/childbirth + scattered petechiae over trunk, UE's, & LE's + low Hb + platelet count of 20,000 + BM aspirate shows megakarocytes
what is the most appropriate next step in management?