Compared with the vast number of mitochondria in an embryo, the
number of mitochondria in an ovum is relatively small. Might such
an ooplasmic mitochondrial bottleneck present an opportunity for
therapy or cure?
a)It may be possible to cure it by increasing mitochondria
number in any way.
b)It may be possible to alter the heteroplasmic ratio by
favoring replication of mitochondria.
c)It may be possible to alter the heteroplasmic ratio by
microinjection of mitochondria.
d)No, there is no opportunity.