Enolase catalyzes a reaction in both the glycolytic pathway and the gluconeogenic pathway. In glycolysis, the reaction is catalyzed in the direction 2PG (2-phosphoglycerate) —> PEP (phosphoenolpyruvate), and in gluconeogenesis, the reaction is catalyzed in the direction PEP —> 2PG. The enzyme is able to catalyze this reaction in both directions because ____________________.
