The following paragraphs describe the first three reactions of a metabolic pathway. Fill in the blanks by moving words to the appropriate blanks. Note that a single red X will appear if you answer any of the blanks incorrectly. Feedback will be placed next to a blank that is incorrectly filled. it all the terms wil be placed.
In reaction 1 of the Krebs cycle, acetyl-CoA formed in the pyruvate dehydrogenase reaction condenses with the four-carbon compound _______ to form ______ with the elimination of coenzyme A. Since the product has three carboxyl groups, this pathway is referred to as the ________cycle.
In reaction 2 of the Krebs cycle, this product then undergoes ________ to form _______ . The enzyme is called aconitase because the compound cis-aconitate is a(n)_________ of the reaction.
Reaction 3 eliminates CO2 to form the 5-carbon dicarboxylic acid_______ . Oxidation also occurs, with electrons transferred from the substrate to __________ . Consequently this reaction is an oxidative decarboxylation.
