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HELPPPP RNN PLSS How did Constantine change the lives of Christians living in his empire? Responses He legalized Christianity in his empire. He legalized Christianity in his empire. He persecuted Christians, often through crucifixion. He persecuted Christians, often through crucifixion. He wrote the epistles, spreading the word of God. He wrote the epistles, spreading the word of God. He supported the Zealots who defended Christianity.