why is gene expression typically regulated at the transcriptional level in prokaryotes? question 2 options: translation occurs as a transcript is being synthesized; therefore controlling transcription has a large effect than controlling translation. it takes multiple transcripts to produce a single protein, so it is energetically favorable to prevent transcription. transcription is a simpler process than translation, and therefore it is easier to control. in prokaryotes, genes are found in operons, and therefore must be transcriptionally regulated.