The acetylation state of the amino terminal tails of histones in the nucleosomes incorporated into a region of chromatin affects the chromatin condensation state. Generally, A. hypophosphorylation of the histones at the promoter region typically leads to an active transcription state. B. hypomethylation of the histones at the promoter region typically leads to an active transcription state. C. hypoacetylation of the histones at the promoter region typically leads to an active transcription state. D. hyperacetylation of the histones at the promoter region typically leads to an active transcription state.
