Turnover number (kcat) is 1. the ratio of the rate constants for the formation of ES and of product. 2. for a mutant enzyme can change without any change in the Km of the reaction. 3. has units of substrate concentration. 4. is the number of molecules of substrate converted per unit time per molecule of enzyme. 5. is inversely related to how fast the reaction is. choose the number that best explains kcat.