Which of the following is NOT a source of the hyperosmotic interstitial fluid that surrounds the loop of Henle?
A.The ascending loop of Henle is very permeable to water, but not ions like sodium and chloride, therefore water diffuses out at a high rate into the interstitial fluid.
B.The epithelial cells of the thick segment of the loop of Henle actively transport some of the remaining sodium and chloride out of the filtrate and into the interstitial fluid of the medulla.
C.Some urea that is present in the filtrate diffuses out of the collecting ducts and into the inner medulla interstitial fluid.
D.The ascending loop of Henle is very permeable to ions like sodium and chloride, but not water, therefore ions diffuse out at a high rate into the interstitial fluid.